In an RV 48 volts is all about running an air conditioner (or two) because feeding a 48v inverter requires 1/4 of the amperage of a 12v system to make the same AC power. It still requires a big battery bank which has been made feasible these days with lithium batteries, but at a significant cost.
But it comes with other complications and costs. You would also need a DC-DC converter to get back to 12v (because you would no longer have a big 12v battery bank), and it would have to be fairly robust to power the systems that draw higher amps (jacks, slides etc). You would also have to re-wire your breaker panels so the inverter powers the air conditioner(s) - not a big deal but another chore. And of course there’s the cost of the new inverter/charger and depending on what you now have, new solar charge controllers. Also since you have 12v panels, you’d have to re-configure your array to feed 48v to your MPPT(s).
But if you’re not going to invest in a big battery bank and run an air conditioner (or two), 48v doesn’t seem to have any advantage, other than greater efficiency, but that benefit seems nominal in this application. And since you’re converting to lithium anyway, you could still have the rest as a future goal and approach the project incrementally.